Guidewire perforation is a common complication of PCI which can be lifethreatening.Simple Coiling can seal off the perforation &save life . But more importantly is to avoid wire perforation by changing stiffer CTO wire to soft wire after wire crossing. Rescue toolkits such as coil , cover stent, iv protamine sulphate pericardial tapping set shall be on standby. at anytime of PCI.